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      《Journal of Xuzhou Medical University》 2019-03
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      Analysis of abdominal adipose distribution in healthy adult males of different ethnic groups in the plateau area by multi-modal analysis of MSCT

      ZHANG Yifan;BAI Zhenzhong;YANG Yanqing;GE Rili;Department of Nuclear Medicine,Qinghai Provincial People's Hospital;Research Center for High Altitude Medicine;Qinghai-Utah Joint Research Key Lab for High Altitude Medicine;  
      Objective To explore the differences and influencing factors of abdominal subcutaneous adipose tissue(SAT) distribution in different ethnic groups in the plateau area by multi-slice spiral CT( MSCT) multi-modal analysis technique. Methods MSCT multi-modality work place(MMWP) technique was used to measure SAT and visceral adipose tissue(VAT) in healthy adult males of different ethnic groups in the plateau area. The distribution of abdominal fat in these subjects at different altitudes was analyzed. Results There was no significant difference in subcutaneous fat volume( SV) between Tibetan and Hui ethnic groups and Han nationality(P 0.05), and visceral fat volume(VV)and VV/SV + VV in Tibetan ethnic group were lower than those in Han nationality(P = 0.004,0.01). There was no significant difference in VV and VV/SV + VV(%) between Hui ethnic group and Han nationality(P0.05). Compared with the high altitude groups, the VV/SV + VV(%) in high altitude groups was lower than that in low altitude groups(P =0.028, 0.022, 0.017). There were negative correlations between VV/SV + VV(%) and altitude in Han, Tibet and Hui nationality(P = 0. 024, 0. 049, 0. 005). Conclusions MMWP technique can provide a comprehensive assessment of abdominal fat distribution by accurately measuring the volume of fat in various parts of the abdomen. Through long-term genetic adaptation to plateau environment, visceral fat in Tibetan population accounts for a small volume of total abdominal fat. The abdominal fat distribution is related to hypoxia and cold environment. With the increase of altitude, the oxygen concentration in the atmosphere and temperature decrease, visceral fat accounted for the total abdominal fat volume decrease.
      【Fund】: 国家自然科学基金(31571231)
      【CateGory Index】: R339.5
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